josh owens
biology
assistant professor
biography
josh owens was raised in huntsville, alabama. following a family legacy, josh attended lipscomb where he majored in molecular biology and graduated in 2016. after lipscomb, josh attended emory university where he earned his phd in immunology and molecular pathogenesis in 2021. during his time at emory, josh was awarded the ruth l. kirschstein national research service award (nrsa, f31) by the national cancer institute. in addition to his nrsa, josh published 17 peer-reviewed articles on topics including cancer immunology, the microbiome, fat metabolism, and covid-19. of note, josh helped lead a joint discovery of a novel microbially produced molecule, delta-valerobetaine. this discovery was the cover of the journal nature metabolism when it was published. at lipscomb, josh leads a research team that is currently funded by the christian scholars’ foundation’s junior faculty grant (2022). his lab is interested in the role of fat metabolism in exacerbating cancer. additionally, his lab is actively pursuing the discovery of novel molecules that effect fat metabolism and may be utilized to treat cancer or obesity. josh chose to come to lipscomb as he is passionate about the mission of lipscomb and desires to be an advocate for his students to help propel them to graduate school, professional school, or the workforce.
josh met his wife erin while still in high school and they have been married since 2017. they have one daughter, piper, who was born in may 2022. in his free time, josh enjoys reading, running, woodworking, and gardening.
academic degrees
b.s. in molecular biology – 世界杯2022预选赛录像回放
(2016)
phd in immunology and molecular pathogenesis – emory university (2021)
academic department
biology
- undergraduate courses:
- graduate courses:
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biomolecular lab 2
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capstone
journal articles:
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malik at,, yu m, darby tm, vaccaro c, li j, owens ja, hsu e, adams j, weitzmann mn, jones rm, and r pacifici (2018) the microbial metabolite butyrate stimulates bone formation via t regulatory cell-mediated regulation of wnt10b expression. immunity. dec (2018);49(6):1116-1131. pmid:30446387.
- darby tm, owens ja, saeedi bj, luo l, matthews jd, robinson bs, crystal r. naudin cr, and rm jones (2019) lactococcus lactis sp. cremoris is an efficacious beneficial bacterium that limits tissue injury in the intestine. iscience. 2019 feb 22;12:356-367. pmid:30739017
- matthews jd, owens ja, naudin cr, saeedi bj, alam a, reedy ar, hinrichs b, sumagin r, neish as, and rm jones. (2019) neutrophil-generated reactive oxygen orchestrates protein signaling during intestinal epithelium wound repair. american journal of pathology. vol. 189, issue 11, nov. (2019), pmid:31472109
- saeedi bj*, liu kh*, owens ja, hunter-chang s, camacho mc, eboka ru, robinson bs, chandrasekharan b, baker nf, darby tm, jones rm, jones dp, and as neish. (2020) gut resident lactobacilli activate hepatic nrf2 and protect against oxidative liver injury. cell metabolism. may 5;31(5) *co-first authors pmid:32213347.
- naudin cr, maner-smith k, owens ja, wynn gm, robinson bs, matthews jd, april r. reedy ar, luo l, wolfarth aa, darby tm, ortlund ea and rm jones. (2020) lactococcus lactis subsp. cremoris elicits protection against metabolic changes induced in females by a western-style diet. gastroenterology. aug;159(2):639-651. pmid:32169430
- robinson bs, saeedi bj, arthur cm, owens ja, kamili na, luo l, jones rm, as neish and sr stowell. (2020). galectin-9 is a novel regulator of epithelial restitution. american journal of pathology. aug;190(8):1657-1666; pmid: 32380082
- wolfarth aa, liu x, darby tm, boyer dj, spizman jb, owens ja, chandrasekharan b, naudin cr, hanley kz, robinson bs, ortlund ea, jones rm, and as neish. (2020). proline rich acidic protein-1 (prap1) protects the gastrointestinal epithelium from irradiation-induced apoptosis. cellular and molecular gastroenterology and hepatology. 10(4):713-727. pmid: 32629119
- allen jwl, verkerke h, owens ja, saeedi b, boyer d, s shin, roback jd, neish as and sr stowell. (2020) serum pooling for rapid expansion of anti-sars-cov-2 antibody testing capacity. transfus clin biol. october. pmid: 33096207
- verkerke h, horwath m, saeedi bj, boyer d, allen jw, owens ja, arthur cm, nakahara h, rha j, brown d, normile k, cole l, brierre f, lin h, woods e, isaac j, broder k, wade j, kauffman r, patel r, josephson cd, reynolds s, sherman m, wrammert j, alter d, guarner j, roback jd, neish as, stowell sr. (2021). comparison of antibody class specific sars-cov-2 serology for the diagnosis of acute covid-19. jcm. pmid: 33468605
- ad ho, h verkerke, jw allen, bj saeedi, d boyer, j owens, s shin, m horwath, k patel, a paul, sc wu, s chonat, p zerra, c lough, jd roback, a neish, cd josephson, cm arthur, sr stowell. (2021). an automated approach to determine antibody endpoint titers for covid-19 by an enzyme-linked immunosorbent assay. immunohematology. pmid: 33962490
- hans werkerke, bejan j saeedi, darra boyer, jerry w allen, joshua owens, sooncheon shi, michael horwath, kashyap patel, anu paul, shang-chuen wu, jianmei wang, alex ho, cheryl l maier, patricia e. zerra, satheesh chonat, connie m. arthur, john d roback, andrew s neish, christopher lough, cassandra d josephson, sean r stowell. (2021) are we forgetting about iga? a re-examination of coronavirus disease 2019 convalescent plasma. transfusion. pmid: 34041759
- liu kh*, owens ja*, saeedi b*, cioffi c, bellissimo mp, naudin cr, darby tm, druzak s, maner-smith k, orr m, hu x, fernandes j, camacho m, hunter-chang s, van insberghe d, ma c, ganesh t, yeligar s, uppal k, go y, alvarez ja, vos mb, ziegler tr, jones rm, ortlund ea, neish as, and dp jones. (2021) microbial metabolite delta-valerobetaine is a diet-dependent obesogen. nature metabolism. *co-first authors. pmid: 34931082
- owens ja, saeedi bj, naudin cr, hunter-chang s, barbian me, eboka ru, askew lc, darby tm, robinson bs, and rm jones. (2021). lactobacillus rhamnosus gg orchestrates an anti-tumor immune response. cellular and molecular gastroenterology and hepatology. cmgh-d-21-00071. pmid: 34111601
- barbian me, owens ja, naudin cr, luo l and rm jones. (2021). butyrate supplementation to pregnant mice elicits cytoprotection against colonic injury in the offspring. pediatric research. pmid: 34616000
- chandrasekharan b, boyer dj, owens ja, wolfarth aa, johnson a, saeedi bj, dhere t, iskander h, neish as. (2021). intracolonic neuropeptide y y1 receptor inhibition attenuates intestinal inflammation in murine colitis and cytokine release in ibd biopsies. inflamm bowel dis. pmid: 34613372
book chapters:
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owens ja, and rm jones. (2021). methods molecular biology, vol. 2237, kelly c. whittaker and ruo-pan huang (eds): antibody arrays, 978-1-0716-1063-3, (chapter 21) immune cell isolation from murine intestine for antibody array analysis. antibody arrays: methods and protocols. 2237:247-256. pmid: 33237424
reviewed articles:
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khan rn, maner-smith k, owens ja, barbian me, jones rm and cr naudin (2021) at the heart of microbial conversations: endocannabinoids and the microbiome in cardiometabolic risk. gut microbes. pmid: 33896380
poster presentation:
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owens ja and jh lowrance. short chain fatty acids stimulation of tlr4 expression in intestinal epithelial cells asm kentucky-tennessee branch annual meeting; poster presentation. september 2015.
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owens ja, saeedi bj, eboka ru, robinson bs, and rm jones. immunomodulatory mechanism of lactobacillus-induced attenuation of colitis-associated carcinoma. the gastrointestinal tract xviii conference: integrated biology of the gi super-organ. steamboat springs, colorado. july 2019.
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owens ja, bejan j saeedi, sarah hunter-chang, crystal r naudin, richard u eboka, brian s robinson, and rheinallt m. jones. the human commensal lactobacillus rhamnosus gg orchestrates an anti-tumor immune response. american association for cancer research virtual meeting. june 2020.
oral presentation:
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owens ja and jh lowrance. short-chain fatty acids up-regulate innate immune responses in intestinal epithelial cells. 世界杯2022预选赛录像回放
’s student scholars symposium. april 2016.
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owens ja, saeedi bj, trevor darby tm, rheinallt jones. the influences of probiotics during colitis and colitis-associated carcinomas. experimental biology 2018. april 2018.
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owens ja, saeedi bj, naudin cr, darby tm, and rm jones. elucidating the cell signaling pathways for epithelial restitution of a novel probiotic. experimental biology 2019. april 2019.
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owens ja, saeedi bj, hunter-chang s, naudin cr, eboka ru, robinson bs, and rm jones. the human commensal lactobacillus rhamnosus gg orchestrates an anti-tumor immune response. division student advisory council (dsac) emory university. january 2020.
invited seminars: